Coronary Perfusion Versus Cold Ischemic Arrest During Aortic Valve Surgery A Randomized Study

摘要: Sixty-four randomized patients undergoing primary, isolated, scheduled, prosthetic aortic valve replacement were studied to determine the safety of coronary perfusion and mild hypothermia (31 patients) cold ischemic arrest (33 patients). Cardiac performance, metabolism, isoenzyme release electrocardiogram early postoperatively. No differences greater than expected by chance found between two groups; however, difference group means several hemodynamic variables was significantly larger experimental error. Combined abnormalities creatine phosphokinase (CPK) lactic dehydrogenase (LDH) heart-specific isoenzymes, indicative myocardial necrosis, in 33 48 (68.7%) so studied. The incidence similar both study groups. In 14 52 (27%) with electrocardiographic studies, changes new infarction or ischemia demonstrated, but no groups were...