African swine fever virus genome content and variability.

作者: L. K. Dixon , S. A. Baylis , S. Vydelingum , S. R. F. Twigg , J. M. Hammond

DOI: 10.1007/978-3-7091-9300-6_15

关键词: BiologyVirulenceOpen reading frameVirologySequence (medicine)ORFSComplete sequenceAfrican swine fever virusDNAGenome

摘要: A 55 kilobase pair (kb) region from the right end of virulent African swine fever virus isolate, Malawi LIL20/1, has been sequenced. The 68 major open reading frames (ORFs) encoded are generally closely spaced and read both DNA strands across complete sequence. Comparison amino acid sequences predicted ORFs with sequence databases identified 15 which encode proteins that similar to known function. Two homologous copies multigene family 360 (MGF360) one ORF is 110 (MGF110). Both these families have described previously [6, 31].

参考文章(67)
E. Viñuela, African swine fever virus. Current Topics in Microbiology and Immunology. ,vol. 116, pp. 151- 170 ,(1985) , 10.1007/978-3-642-70280-8_8
M. B. Pensaert, Virus infections of porcines. Elsevier Science. ,(1989)
J W McVicar, Quantitative aspects of the transmission of African swine fever American Journal of Veterinary Research. ,vol. 45, pp. 1535- 1541 ,(1984)
Gholamreza Darai, Molecular Biology of Iridoviruses ,(2011)
Yechiel Becker, Julia Hadar, Developments in veterinary virology Nijhoff. ,(1985)
G R Thomson, The epidemiology of African swine fever: the role of free-living hosts in Africa. Onderstepoort Journal of Veterinary Research. ,vol. 52, pp. 201- 209 ,(1985)
S S Broyles, B S Fesler, Vaccinia virus gene encoding a component of the viral early transcription factor. Journal of Virology. ,vol. 64, pp. 1523- 1529 ,(1990) , 10.1128/JVI.64.4.1523-1529.1990
Fernando Almazán, Javier M Rodríguez, Germán Andrés, R Pérez, Eladio Viñuela, José F Rodríguez, None, Transcriptional analysis of multigene family 110 of African swine fever virus. Journal of Virology. ,vol. 66, pp. 6655- 6667 ,(1992) , 10.1128/JVI.66.11.6655-6667.1992
M. J. Bishop, C. J. Rawlings, Nucleic acid and protein sequence analysis : a practical approach IRL Press. ,(1987)
L. K. Dixon, P. J. Wilkinson, K. J. Sumption, F. Ekue, Diversity of the African swine fever virus genome. Diversity of the African swine fever virus genome.. pp. 271- 295 ,(1990) , 10.1007/978-1-4613-1615-2_13