Early results with the LARIAT device for left atrial appendage exclusion in patients with atrial fibrillation at high risk for stroke and anticoagulation.

摘要: Objectives To evaluate early outcomes of left atrial appendage (LAA) closure via a percutaneous LAA ligation approach with the SentreHeart LARIAT™ snare device. Background Atrial fibrillation increases risk stroke 4–5 fold, which can have devastating outcomes. Exclusion is believed to decrease embolic stroke. Methods Twenty-seven patients fibrillation, high stroke, and contraindication or intolerance for anticoagulation therapy underwent LARIAT device. Initial was confirmed TEE contrast fluoroscopy. Results The acute procedural success 92.6%. One patient sustained perforation treated conservatively. The surgically next day. In one attempt advance over unsuccessful. Patients were followed mean 4 months. Preserved 45 day follow-up in 22 25 completing procedure. Peri-operative complications included three cases pericarditis case periprocedural CVA due thrombus formation on transseptal sheath. During follow-up, there thought be noncardioembolic pleural effusion. There no deaths. Conclusions These results show that exclusion achieved successfully an acceptable rate short-term complications. Further studies longer are needed determine whether lowers long-term thromboembolic events AF contraindications anticoagulation. © 2015 Wiley Periodicals, Inc.