Histopathological trephine biopsy findings in cases of 'dry tap' bone marrow aspirations.

作者: Colombano Mt , Navone R

DOI:

关键词: HistologyBiopsyPathologyBone marrow fibrosisNormal boneTrephine biopsyMedicineImmature cellsBone marrow

摘要: Out of 3,173 bone marrow biopsies, we found 138 cases (4.3%) 'dry tap' aspirations: 35/218 (16%) acute leukemias, 44/445 (9.8%) myeloproliferative syndromes, 29/328 (8.8%) malignant lymphomas and Hodgkin's diseases, 10/208 (4.8%) myelomas 10/74 (13.5%) metastatic carcinomas. Histology showed that the most common changes associated with scanty yield aspirations were fibrosis (patchy or diffuse) hypercellularity (especially if due to immature cells). None normal by trephine biopsy. It is concluded finding a should never be dismissed as being faulty technique always needs

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