Influence of trehalose 6,6′-dimycolate (TDM) during mycobacterial infection of bone marrow macrophages
作者： Jessica Indrigo , Robert L. Hunter , Jeffrey K. Actor
DOI: 10.1099/00221287-148-7-1991
关键词: Immunology 、 Microbiology 、 Mycobacterium tuberculosis 、 Cytokine 、 Trehalose 、 Intracellular 、 Cord factor 、 Secretion 、 Chemokine 、 Biology 、 Macrophage
摘要: … BMMs infected with delipidated MTB did not produce IL-6 initially; however, by 24h after … In this study, C57BL\6 BMMs infected with native MTB produced copious amounts of IL-6. Fur…
thermoscientific.com参考文章(31)
Actor Jk, Watson Ve, Hunter Rl, Dasgupta A, Wells A, Leonard Cd, Jagannath C, Cytokine mRNA expression and serum cortisol evaluation during murine lung inflammation induced by Mycobacterium tuberculosis. Combinatorial Chemistry & High Throughput Screening. ,vol. 3, pp. 343- 351 ,(2000)
I M Orme, E R Rhoades, A M Cooper, D M Getzy, J E Callahan, A D Roberts, THE ROLE OF INTERLEUKIN-12 IN ACQUIRED IMMUNITY TO MYCOBACTERIUM TUBERCULOSIS INFECTION Immunology. ,vol. 84, pp. 423- 432 ,(1995)
T. I. A. Roach, J. M. Blackwell, D. Chatterjee, C. H. Barton, Macrophage activation: lipoarabinomannan from avirulent and virulent strains of Mycobacterium tuberculosis differentially induces the early genes c-fos, KC, JE, and tumor necrosis factor-alpha. Journal of Immunology. ,vol. 150, pp. 1886- 1896 ,(1993)
S. M. Ekizlerian, C. L. Silva, R. A. Fazioli, Role of cord factor in the modulation of infection caused by mycobacteria. American Journal of Pathology. ,vol. 118, pp. 238- 247 ,(1985)
T K VanHeyningen, D G Russell, H L Collins, IL-6 produced by macrophages infected with Mycobacterium species suppresses T cell responses. Journal of Immunology. ,vol. 158, pp. 330- 337 ,(1997)
A Yoshida, Y Koide, Arabinofuranosyl-terminated and mannosylated lipoarabinomannans from Mycobacterium tuberculosis induce different levels of interleukin-12 expression in murine macrophages. Infection and Immunity. ,vol. 65, pp. 1953- 1955 ,(1997) , 10.1128/IAI.65.5.1953-1955.1997
I P Oswald, C M Dozois, J F Petit, G Lemaire, Interleukin-12 synthesis is a required step in trehalose dimycolate-induced activation of mouse peritoneal macrophages. Infection and Immunity. ,vol. 65, pp. 1364- 1369 ,(1997) , 10.1128/IAI.65.4.1364-1369.1997
B. J. Spargo, L. M. Crowe, T. Ioneda, B. L. Beaman, J. H. Crowe, Cord factor (alpha,alpha-trehalose 6,6'-dimycolate) inhibits fusion between phospholipid vesicles. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 737- 740 ,(1991) , 10.1073/PNAS.88.3.737
PE Kolattukudy, Norvin D Fernandes, AK Azad, Ann Marie Fitzmaurice, Tatiana D Sirakova, None, Biochemistry and molecular genetics of cell-wall lipid biosynthesis in mycobacteria Molecular Microbiology. ,vol. 24, pp. 263- 270 ,(1997) , 10.1046/J.1365-2958.1997.3361705.X
Jeffrey K. Actor, Margaret Olsen, Chinnaswamy Jagannath, Robert L. Hunter, Relationship of survival, organism containment, and granuloma formation in acute murine tuberculosis. Journal of Interferon and Cytokine Research. ,vol. 19, pp. 1183- 1193 ,(1999) , 10.1089/107999099313136