作者: Hewan Belete , Lindsay Godin , Randolph Stroetz , Rolf Hubmayr
DOI: 10.1159/000272052
关键词: Cell 、 DNA repair 、 Cell biology 、 Electroporation 、 Biology 、 Lesion 、 Ventilator-associated lung injury 、 Cell membrane 、 Cell type 、 Lung injury 、 Pathology
摘要: Cell wounding, that is a loss of plasma membrane integrity, common everyday occurrence in load bearing organs such as muscle, skin, and bone. In general, these injuries trigger adaptive responses to either restore homeostasis or protect the cells from further damage. The ability integrity after injury critical for cell survival all possess means do so. However, probability wound repair depends on type, well size nature lesion. Several vitro experimental models have been developed simulate specific stresses experience vivo. Motivated by our interest studying mechanisms relevant ventilator associated lung injury, we review some most frequently used wounding present new data pertaining alveolar epithelium.