Voltammetric study on the interaction of heparin with toluidine blue, and its analytical application
作者： Xiu Ying Peng , Hong Qun Luo , Nian Bing Li
DOI: 10.1007/S00604-006-0641-7
关键词: Linear range 、 Heparin 、 Analytical chemistry 、 Cyclic voltammetry 、 Voltammetry 、 Toluidine 、 Nuclear chemistry 、 Electrochemistry 、 Detection limit 、 Chemistry 、 Polyelectrolyte
摘要: The interaction of heparin with toluidine blue (TB) was studied by voltammetry. In pH 5.8 Britton-Robinson (BR) buffer, heparin, which is negatively charged, easily binds to the positively charged TB form a polyelectrolyte complex. Due formation complex, well-defined redox peaks at glass carbon electrode decreased correspondingly without movement peak potential after addition heparin. reaction conditions were optimized carefully. Based on decrease current solution, new electrochemical analytical method established for linear range from 1.0 20.0 µg mL−1 and detection limit 0.44 mL−1. relative standard deviation (RSD) five parallel determinations 10.0 1.07%. This applied determination in sodium injection samples satisfactory results.
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sci-hub.se 参考文章(24)
J. Hirsch, T. Wendt, P. Kuhly, W. Schaffartzik, Point-of-care testing apparatus. Measurement of coagulation. Anaesthesia. ,vol. 56, pp. 760- 763 ,(2001) , 10.1046/J.1365-2044.2001.02131.X
S.A. Ampofo, H.M. Wang, R.J. Linhardt, Disaccharide compositional analysis of heparin and heparan sulfate using capillary zone electrophoresis Analytical Biochemistry. ,vol. 199, pp. 249- 255 ,(1991) , 10.1016/0003-2697(91)90098-E
Shu Ching. Ma, Victor C. Yang, Mark E. Meyerhoff, Heparin-responsive electrochemical sensor: a preliminary study. Analytical Chemistry. ,vol. 64, pp. 694- 697 ,(1992) , 10.1021/AC00030A023
Hong Qun Luo, Shao Pu Liu, Nian Bing Li, Zhong Fang Liu, Resonance Rayleigh scattering, frequency doubling scattering and second-order scattering spectra of the heparin–crystal violet system and their analytical application Analytica Chimica Acta. ,vol. 468, pp. 275- 286 ,(2002) , 10.1016/S0003-2670(02)00633-5
I Němcová, P Rychlovský, M Havelcová, M Brabcová, Determination of heparin using flow injection analysis with spectrophotometric detection Analytica Chimica Acta. ,vol. 401, pp. 223- 228 ,(1999) , 10.1016/S0003-2670(99)00472-9
Shaopu Liu, Hongqun Luo, Nianbing Li, Zhongfang Liu, Wenxu Zheng, Resonance Rayleigh scattering study of the interaction of heparin with some basic diphenyl naphthylmethane dyes. Analytical Chemistry. ,vol. 73, pp. 3907- 3914 ,(2001) , 10.1021/AC001454H
Peter Mikuš, Iva Valášková, Emil Havránek, Analytical characterization of heparin by capillary zone electrophoresis with conductivity detection and polymeric buffer additives Journal of Pharmaceutical and Biomedical Analysis. ,vol. 36, pp. 441- 446 ,(2004) , 10.1016/J.JPBA.2004.07.017
Qingcai Jiao, Qian Liu, Mechanism of Interference and Azur A Response in the Heparin Assay Analytical Letters. ,vol. 31, pp. 1311- 1323 ,(1998) , 10.1080/00032719808002868
Tzong-Jih Cheng, Tsun-Mei Lin, Tsui-Hsun Wu, Hsien-Chang Chang, Determination of heparin levels in blood with activated partial thromboplastin time by a piezoelectric quartz crystal sensor Analytica Chimica Acta. ,vol. 432, pp. 101- 111 ,(2001) , 10.1016/S0003-2670(00)01346-5
Tzong-Jih Cheng, Tsun-Mei Lin, Hsien-Chang Chang, Physical adsorption of protamine for heparin assay using a quartz crystal microbalance and electrochemical impedance spectroscopy Analytica Chimica Acta. ,vol. 462, pp. 261- 273 ,(2002) , 10.1016/S0003-2670(02)00335-5