Determination of heparin levels in blood with activated partial thromboplastin time by a piezoelectric quartz crystal sensor
作者： Tzong-Jih Cheng , Tsun-Mei Lin , Tsui-Hsun Wu , Hsien-Chang Chang
DOI: 10.1016/S0003-2670(00)01346-5
关键词:
摘要: Abstract A piezoelectric quartz crystal (PQC) sensor, possessing a sensitive frequency response to viscoelastic variations of substance loading on an electrode surface, was used determine both whole blood activated partial thromboplastin time (WBaPTT) and plasma (PLaPTT) induced by anticoagulant heparin. The PQC sensor results showed linear relationship between WBaPTT (or PLaPTT) heparin levels in clinically relevant concentrations (0–0.4 unit/ml). Mean individual R2 (= 0.9491) for regressive curve adequately shown. method can be evaluate the effect through determination owing comparable sensitivity (P
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