Antimicrobial treatment and outcomes of critically ill patients with OXA-48like carbapenemase-producing Enterobacteriaceae infections

作者: Warren Lowman , Gunter Schleicher

DOI: 10.1016/J.DIAGMICROBIO.2014.09.023

关键词: Intensive care medicineCritically illMedicineOdds ratioIntensive care unitImproved survivalHealth evaluationCarbapenemase-Producing EnterobacteriaceaeAntimicrobialCarbapenem

摘要: We report on the clinical characteristics, antimicrobial therapy, and outcomes of 20 critically ill patients with severe OXA-48like infections. Carbapenem-based therapy demonstrated improved survival (odds ratio = 5.0) as compared non-carbapenem therapy. Risk factors for mortality included Acute Physiology Chronic Health Evaluation III score length stay, highlighting significant influence comorbidities severity underlying illness outcomes.

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