Clinical studies of Platinum Coordination compounds in the treatment of various malignant diseases.

作者: MacLellan A , King Jj , Khan A , Hill Jm , Loeb E

DOI:

关键词: Tumor regressionPlatinum CompoundOncologyPlatinumInternal medicineInorganic chemistryMedicineChemotherapyClinical trial

摘要: Following the prior work of Rosenberg et al, and VanCamp, Speer we started clinical trials with cis-dichlorodiammineplatinum(II) in April 1971. Marked tumor regression was noted several malignant diseases these initial studies which were reported at Chemotherapy Congress Prague, August At present time over 178 patients have been treated wihhis durg for a variety conditions. Approximately half received platinum compound alone other it combination four chemotherapeutic agents...

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