Family History of Hypertension and Red Cell Cation Transport in High School Students

摘要: High school students who had at least one parent with hypertension (n = 22) were compared to schoolmates of the same age a negative family history in parents 21). We investigated both groups maximal rate ouabain-sensitive Na pump and Na-K cotransport nystatin-loaded cells Lii-Nao countertransport lithium-loaded cells. The two significantly different only sum net transport mediated by cotransport. mean diastolic blood pressure positive group was higher. With control for difference no longer significant; it remains uncertain if represents "over-adjustment'. finding higher these adolescents are increased risk future hypertension, yet currently well within normal range, suggests that abnormal sodium metabolism may be useful marker appears early pathogenesis this disease.