Carcinome hépatocellulaire et transplantation hépatique : état des lieux

摘要: Hepatic transplantation offers the best treatment for cure hepatocellular carcinoma arising in cirrhotic liver as long patients and indications are carefully selected. The Milan criteria which became established 1990's showed that results obtained when there three or fewer nodules less than 3 cm size, a single nodule five cm. size. Today, these seem to be too restrictive, surgery can extended by employing based on macroscopic findings, histology, even molecular biology. It is necessary not only better define limits of therapy but also keep close watch awaiting transplant prevent exclusion from list due tumor progression. Results improved decreasing late recurrence with an optimal postoperative immunosuppressive regimen adjuvant chemotherapy. choice using living donor transplanting marginal quality should weighed against characteristics anticipated waiting period liver. increasing incidence imposes need offer curative more we able do under current circumstances. strategies cancer multidisciplinary start; use all available tools including evaluated multicentric studies.