Living-donor liver transplantation for hepatocellular carcinoma.

摘要: In cadaveric liver transplantation, the Milan criteria have been accepted as selection for hepatocellular carcinoma (HCC) patients in considering organ allocation. However, situation is different living-donor transplantation (LDLT), which donor has a strong preference altruism. The authors describe herein their experience with LDLT HCC using patient criteria. From February 1999 to March 2002, right lobe was performed 56 HCC. authors' exclusion included only those extrahepatic metastasis or vascular invasion detected during preoperative evaluation. Thirty (54%) were tumor, node, metastases stage IVa and 25 (45%) did not meet at time of LDLT. follow-up period 1 39 months (median, 11 months). overall survival rates 3 years 73% 55%, respectively, latter significantly lower than that adult without (71% years). Fourteen died because postoperative complications tumor recurrence. Thirty-six survived recurrence six had Among recurrence, four 36 after analysis who longer 19 20 within 15 beyond also 33 12 months) three five alive Histopathologic grading microscopic portal venous significant negative impact on an effective treatment uncontrollable carcinoma. Because many are necessary save advanced