Living donor liver transplantation for hepatocellular carcinoma: a single center analysis of outcomes and impact of different selection criteria.

摘要: Summary We examined the outcomes of patients who received living donor liver transplantation (LDLT) for HCC comparing impact up-to-seven criteria and Asan Criteria (AC) with Milan (MC). Between July 2004 2009, 175 consecutive LDLT, there were 45 HCC. Forty completed 12 months follow-up enrolled. In search highest number expansion, we selected AC as extended criteria. Patients divided into having tumors within MC, beyond MC Beyond (BC) groups. With a median 46 months, overall 1, 3, 5 years survival was )90%, )81%, )70%, respectively. AC, estimated mean 49.8 vs. 40.5 BC group (P = 0.2). Disease-free significantly higher in group; 48.0 38.6 0.04). Preoperative AFP level >400 poor tumor differentiation factors adversely effecting recipient survival. On multivariate analysis, presence 0.018 RR: 2.48) only independent predictor Extension size to is feasible, without compromising outcomes; however, associated worse after LDLT.