Cytoreductive surgery for melanoma.

摘要: Cytoreductive surgery represents a therapeutic attempt to improve patient outcomes by reducing overall tumor burden render postsurgical therapy effective or at least increase its effectiveness. The intent of cytoreduction differs from palliative curative-intent for oligometastatic melanoma. Both and attempted curative resection have important roles play in the management patients with melanoma that has spread beyond regional nodes recurred "in transit" between primary nodal basin. To date, however, no evidence shows cytoreductive offers any meaningful benefit metastatic melanoma, and, outside clinical trial, there is role adjuvant vaccine after complete not proved be efficacious trials, so little reason believe use currently available immunotherapy strategies will enhanced incomplete resections.