作者: Kentaro Ohkuni , Katsumi Kitagawa
DOI: 10.4161/TRNS.20884
关键词: Centromere 、 Promoter 、 Eukaryotic transcription 、 Enhancer 、 Biology 、 Genetics 、 General transcription factor 、 TCF4 、 Transcription factories 、 TAF2
摘要: Centromeres are specialized chromosomal loci that essential for proper chromosome segregation. Recent data show a certain level of active transcription, regulated by transcription factors Cbf1 and Ste12, makes direct contribution to centromere function in Saccharomyces cerevisiae. Here, we discuss the requirement at centromeres.