Dual cascade isothermal amplification reaction based glucometer sensors for point-of-care diagnostics of cancer-related microRNAs.

作者: Chao Zhao , Mengjia Xu , Pan Fu , Shu Xing , Yang Zhao

DOI: 10.1039/D1AN00037C

关键词: InvertaseSubstrate (chemistry)Chain reactionDetection limitCombinatorial chemistryLoop-mediated isothermal amplificationPeptide nucleic acidNucleic acidChemistryOrders of magnitude (mass)

摘要: … between CHA and HCR, the sensor is able … HCR) and is capable of distinguishing single-base mismatched sequences. Thus the convenient, sensitive, robust and low-cost PGM sensor …

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