作者: Jo Kramer-Johansen , Helge Myklebust , Lars Wik , Bob Fellows , Leif Svensson
DOI: 10.1016/J.RESUSCITATION.2006.05.011
关键词: Anesthesia 、 Surgery 、 Clinical trial 、 Intention-to-treat analysis 、 Odds ratio 、 Resuscitation 、 Medicine 、 Prospective cohort study 、 Logistic regression 、 Intensive care 、 Cardiopulmonary resuscitation
摘要: Aims To compare quality of CPR during out-of-hospital cardiac arrest with and without automated feedback. Materials methods Consecutive adult, arrests all causes were studied. One hundred seventy-six episodes (March 2002–October 2003) feedback compared to 108 (October 2003–September 2004) where automatic on was given. Automated verbal visual based measured a prototype defibrillator. Quality the main outcome measure survival reported as specified in protocol. Results Average compression depth increased from (mean ± S.D.) 34 ± 9 38 ± 6 mm (mean difference (95% CI) 4 (2, 6), P < 0.001), median percentage compressions adequate (38–51 mm) 24% 53% (P < 0.001, Mann–Whitney U-test) feedback. Mean rate decreased 121 ± 18 109 ± 12 min−1 (difference −12 (−16, −9), P = 0.001). There no changes mean number ventilations per minute; 11 ± 5 min−1 versus 11 ± 4 min−1 0 (−1, 1), P = 0.8) or fraction time chest compressions; 0.48 ± 0.18 0.45 ± 0.17 −0.03 (−0.08, 0.01), P = 0.08). With intention treat analysis 7/241 control patients discharged alive (2.9%) 5/117 (4.3%) (OR 1.5 CI; 0.8, 3), P = 0.2). In logistic regression cases, witnessed 4.2 1.6, 11), P = 0.004) average (per mm increase) 1.05 1.01, 1.09), P = 0.02) associated hospital admission. Conclusions Automatic improved this prospective non-randomised study arrest. Increased short-term survival. Trial registration ClinicalTrials.gov (NCT00138996), http://www.clinicaltrials.gov/.