Percutaneous Absorption of Nicotinic Acid and Derivatives
作者： Richard B. Stoughton , William E. Clendenning , Doris Kruse
DOI: 10.1038/JID.1960.129
关键词: Biochemistry 、 Related derivatives 、 Penetration (firestop) 、 Percutaneous absorption 、 Nicotinic agonist 、 Chemistry 、 Ether 、 Partition coefficient 、 Chromatography 、 Cell biology 、 Molecular biology 、 Dermatology
摘要: We have utilized a biologic reaction (vasodilation) to measure penetration through the epidermis of nicotinic acid and seven closely related derivatives. also determined partition coefficients absolute solubilities these substances in water ether. A correlation is shown between ease percutaneous absorption given compound relative compounds ether water.
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