Methods and reagents for diagnosing rheumatoid arthrtis

作者: Ryotaro Chiba , Toru Yoshimura

DOI:

关键词: Rheumatoid factorImmunologyProtein levelTest sampleRheumatoid arthritisDermatologyMedicine

摘要: Methods for diagnosing rheumatoid arthritis (RA) are disclosed, using measurement of the CCL8 protein level in a test sample from subject. Testing as an indicator RA can be combined with testing other indicators RA, including clinical assessments, imaging or markers such Rheumatoid factor (RF). used discriminating diseases conditions, evaluating severity RA. Related diagnostic reagents, kits, pharmaceutical compositions, and methods identifying candidate substance therapeutic agent treating also described.

参考文章(95)
John F Marcelletti, Robert M Nakamura, Assessment of serological markers associated with rheumatoid arthritis Clinical and Applied Immunology Reviews. ,vol. 4, pp. 109- 123 ,(2003) , 10.1016/S1529-1049(03)00048-5
G. M. Grass, J. R. Robinson, Sustained- and controlled-release drug delivery systems Drugs and the pharmaceutical sciences. ,vol. 40, pp. 635- 671 ,(1978)
Velizar Tchernev, Stephen F. Kingsmore, Ebenezer Satyaraj, Barry Schweitzer, Qin Fu, Dhavalkumar D. Patel, Immune modulatory activity of human ribonucleases ,(2003)
Cass J. Grandone, Gary Lee Zuck, Stephen L. Herchenbach, Robert J. Nelson, James L. Tyranski, Reagent pack for immunoassays ,(1992)
Michihiro Hide, Kaori Ishii, Hidenori Suzuki, Toshihiko Tanaka, Akio Tanaka, Atopic dermatitis inducer ,(2004)
Jiang Wu, Johannes W. Zolg, Braydon C. Guild, Hua Liao, Michael D. Jones, Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis ,(2002)
Victoria P. Meucci, Mariola B. Zajac, Solubilization reagent for biological test samples ,(1991)