Atopic dermatitis inducer

作者: Michihiro Hide , Kaori Ishii , Hidenori Suzuki , Toshihiko Tanaka , Akio Tanaka

DOI:

关键词:

摘要: An atopic dermatitis inducer binding to a human own IgE antibody and activating mast cells basophiles, which includes purified secretion fraction, or an antigenic molecule determinant in the obtained through following steps of: filtering secretion, removing insoluble matters collecting filtrate; mixing filtrate with ConA-affinity carrier supernatant; separating component having histamine-releasing activity from supernatant by column chromatography. This is effective diagnosing treating dermatitis.

参考文章(15)
Alfonso R. Gennaro, Joseph P. Remington, Remington's pharmaceutical sciences Published in <b>1975</b> in Easton Pa) by Mack. ,(1985)
Sarah Bodary, Thomas D. Wu, Janet Jackman, Hilary Clark, P. Mickey Williams, Jill Schoenfeld, William I. Wood, Nouvelles compositions et methodes de traitement du psoriasis ,(2003)
Ingrid Erika Akerblom, Lynn E. Murry, Human cachexia associated protein ,(1997)
Kazunori Sagawa, Akihiko Kimura, Yoshifumi Saito, Hiroshi Inoue, Seiji Yasuda, Mizuho Nosaka, Tsutomu Tsuji, Production and characterization of a monoclonal antibody for sweat-specific protein and its application for sweat identification. International Journal of Legal Medicine. ,vol. 117, pp. 90- 95 ,(2003) , 10.1007/S00414-002-0341-8
Birgit Schittek, Claus Garbe, Antimicrobially active peptide ,(2002)
Michihiro Hide, Toshihiko Tanaka, Yumi Yamamura, Osamu Koro, Shoso Yamamoto, IgE-mediated hypersensitivity against human sweat antigen in patients with atopic dermatitis. Acta Dermato-venereologica. ,vol. 82, pp. 335- 340 ,(2002) , 10.1080/000155502320624050
S. Rieg, C. Garbe, B. Sauer, H. Kalbacher, B. Schittek, Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions. British Journal of Dermatology. ,vol. 151, pp. 534- 539 ,(2004) , 10.1111/J.1365-2133.2004.06081.X
Birgit Schittek, Rainer Hipfel, Birgit Sauer, Jürgen Bauer, Hubert Kalbacher, Stefan Stevanovic, Markus Schirle, Kristina Schroeder, Nikolaus Blin, Friedegund Meier, Gernot Rassner, Claus Garbe, Dermcidin: a novel human antibiotic peptide secreted by sweat glands Nature Immunology. ,vol. 2, pp. 1133- 1137 ,(2001) , 10.1038/NI732
Hubert Kalbacher, Thomas Flad, Ralf Bogumil, Jonathan Tolson, Birgit Schittek, Claus Garbe, Martin Deeg, Claudia A Mueller, Detection of dermcidin-derived peptides in sweat by ProteinChip technology. Journal of Immunological Methods. ,vol. 270, pp. 53- 62 ,(2002) , 10.1016/S0022-1759(02)00229-6