Genome-wide association study of myelosuppression in non-small-cell lung cancer patients with platinum-based chemotherapy

作者: D Lu , H Shen , S Cao , S Wang , H Ma

DOI: 10.1038/TPJ.2015.22

关键词: Single-nucleotide polymorphismOdds ratioMedicineChemotherapyStage (cooking)Lung cancerImmunologyInternal medicineOncologyStatistical significanceGenome-wide association studyConfidence interval

摘要: … especially myelosuppression. Beyond the impact on quality of life, severe myelosuppression toxicity … to alter the risk of platinum-induced myelosuppression in NSCLC patients. However, …

参考文章(34)
U Grouven, R Bender, Ordinal logistic regression in medical research. Journal of The Royal College of Physicians of London. ,vol. 31, pp. 546- 551 ,(1997)
Birei Furuta, Ayako Harada, Yoko Kobayashi, Ken-ichi Takeuchi, Tetsuyuki Kobayashi, Masato Umeda, Identification and functional characterization of nadrin variants, a novel family of GTPase activating protein for rho GTPases. Journal of Neurochemistry. ,vol. 82, pp. 1018- 1028 ,(2004) , 10.1046/J.1471-4159.2002.01021.X
Sean V. Tavtigian, Jacques Simard, David H.F. Teng, Vicki Abtin, Michelle Baumgard, Audrey Beck, Nicola J. Camp, Arlene R. Carillo, Yang Chen, Priya Dayananth, Marc Desrochers, Martine Dumont, James M. Farnham, David Frank, Cheryl Frye, Siavash Ghaffari, Jamila S. Gupte, Rong Hu, Diana Iliev, Teresa Janecki, Edward N. Kort, Kirsten E. Laity, Amber Leavitt, Gilles Leblanc, Jodi McArthur-Morrison, Amy Pederson, Brandon Penn, Kelly T. Peterson, Julia E. Reid, Sam Richards, Marianne Schroeder, Richard Smith, Sarah C. Snyder, Brad Swedlund, Jeff Swensen, Alun Thomas, Martine Tranchant, Ann-Marie Woodland, Fernand Labrie, Mark H. Skolnick, Susan Neuhausen, Johanna Rommens, Lisa A. Cannon-Albright, A candidate prostate cancer susceptibility gene at chromosome 17p Nature Genetics. ,vol. 27, pp. 172- 180 ,(2001) , 10.1038/84808
Yu Peng, Zheng Li, Shiheng Zhang, Yanli Xiong, Yanping Cun, Chengyuan Qian, Mengxia Li, Tao Ren, Lei Xia, Yi Cheng, Dong Wang, Association of DNA base excision repair genes (OGG1, APE1 and XRCC1) polymorphisms with outcome to platinum‐based chemotherapy in advanced nonsmall‐cell lung cancer patients International Journal of Cancer. ,vol. 135, pp. 2687- 2696 ,(2014) , 10.1002/IJC.28892
Lingmin Hu, Chen Wu, Xueying Zhao, Rebecca Heist, Li Su, Yang Zhao, Baohui Han, Songyu Cao, Minjie Chu, Juncheng Dai, Jing Dong, Yongqian Shu, Lin Xu, Yijiang Chen, Yi Wang, Feng Lu, Yue Jiang, Dianke Yu, Hongyan Chen, Wen Tan, Hongxia Ma, Jiaping Chen, Guangfu Jin, Tangchun Wu, Daru Lu, David C Christiani, Dongxin Lin, Zhibin Hu, Hongbing Shen, None, Genome-Wide Association Study of Prognosis in Advanced Non-Small Cell Lung Cancer Patients Receiving Platinum-based Chemotherapy Clinical Cancer Research. ,vol. 18, pp. 5507- 5514 ,(2012) , 10.1158/1078-0432.CCR-12-1202
Ross Ihaka, Robert Gentleman, R: A Language for Data Analysis and Graphics Journal of Computational and Graphical Statistics. ,vol. 5, pp. 299- 314 ,(1996) , 10.1080/10618600.1996.10474713
Wouter Korver, Claudia Guevara, Yang Chen, Saskia Neuteboom, Rob Bookstein, Sean Tavtigian, Emma Lees, The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the γ‐tubulin complex International Journal of Cancer. ,vol. 104, pp. 283- 288 ,(2003) , 10.1002/IJC.10945
Ninna Richnau, Pontus Aspenström, Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1. Journal of Biological Chemistry. ,vol. 276, pp. 35060- 35070 ,(2001) , 10.1074/JBC.M103540200
Xiaoming Tan, Qihan Wu, Yanyan Cai, Xueying Zhao, Shingming Wang, Zhiqiang Gao, Yang Yang, Xiaoying Li, Ji Qian, Jiucun Wang, Bo Su, Hongyan Chen, Baohui Han, Gening Jiang, Daru Lu, None, Novel Association Between CD74 Polymorphisms and Hematologic Toxicity in Patients With NSCLC After Platinum-Based Chemotherapy Clinical Lung Cancer. ,vol. 15, pp. 67- 78.e12 ,(2014) , 10.1016/J.CLLC.2013.08.006
John Lonsdale, Jeffrey Thomas, Mike Salvatore, Rebecca Phillips, Edmund Lo, Saboor Shad, Richard Hasz, Gary Walters, Fernando Garcia, Nancy Young, Barbara Foster, Mike Moser, Ellen Karasik, Bryan Gillard, Kimberley Ramsey, Susan Sullivan, Jason Bridge, Harold Magazine, John Syron, Johnelle Fleming, Laura Siminoff, Heather Traino, Maghboeba Mosavel, Laura Barker, Scott Jewell, Dan Rohrer, Dan Maxim, Dana Filkins, Philip Harbach, Eddie Cortadillo, Bree Berghuis, Lisa Turner, Eric Hudson, Kristin Feenstra, Leslie Sobin, James Robb, Phillip Branton, Greg Korzeniewski, Charles Shive, David Tabor, Liqun Qi, Kevin Groch, Sreenath Nampally, Steve Buia, Angela Zimmerman, Anna Smith, Robin Burges, Karna Robinson, Kim Valentino, Deborah Bradbury, Mark Cosentino, Norma Diaz-Mayoral, Mary Kennedy, Theresa Engel, Penelope Williams, Kenyon Erickson, Kristin Ardlie, Wendy Winckler, Gad Getz, David DeLuca, Daniel MacArthur, Manolis Kellis, Alexander Thomson, Taylor Young, Ellen Gelfand, Molly Donovan, Yan Meng, George Grant, Deborah Mash, Yvonne Marcus, Margaret Basile, Jun Liu, Jun Zhu, Zhidong Tu, Nancy J Cox, Dan L Nicolae, Eric R Gamazon, Hae Kyung Im, Anuar Konkashbaev, Jonathan Pritchard, Matthew Stevens, Timothèe Flutre, Xiaoquan Wen, Emmanouil T Dermitzakis, Tuuli Lappalainen, Roderic Guigo, Jean Monlong, Michael Sammeth, Daphne Koller, Alexis Battle, Sara Mostafavi, Mark McCarthy, Manual Rivas, Julian Maller, Ivan Rusyn, Andrew Nobel, Fred Wright, Andrey Shabalin, Mike Feolo, Nataliya Sharopova, Anne Sturcke, Justin Paschal, James M Anderson, Elizabeth L Wilder, Leslie K Derr, Eric D Green, Jeffery P Struewing, Gary Temple, Simona Volpi, Joy T Boyer, Elizabeth J Thomson, Mark S Guyer, Cathy Ng, Assya Abdallah, Deborah Colantuoni, Thomas R Insel, Susan E Koester, A Roger Little, Patrick K Bender, Thomas Lehner, Yin Yao, Carolyn C Compton, Jimmie B Vaught, Sherilyn Sawyer, Nicole C Lockhart, Joanne Demchok, Helen F Moore, The Genotype-Tissue Expression (GTEx) project Nature Genetics. ,vol. 45, pp. 580- 585 ,(2013) , 10.1038/NG.2653