Hybridization properties of aromatic peptide nucleic acids: a novel class of oligonucleotide analogues.

作者: Lee D. Fader , Youla S. Tsantrizos

DOI: 10.1021/OL010231Q

关键词: DNAPeptideOligonucleotideRNANucleic acidBiochemistryChemistryNucleobaseNucleic acid thermodynamicsComplementary DNA

摘要: [structure: see text] The synthesis of APNA-PNA chimeras containing all four DNA bases will be described. hybridization properties with and RNA are consistent plausible intramolecular interactions that could preorganize the oligomers in a duplex or triplex structure complementary RNA.

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