l-glutamine Improves Skeletal Muscle Cell Differentiation and Prevents Myotube Atrophy After Cytokine (TNF-α) Stress Via Reduced p38 MAPK Signal Transduction
作者： Matthew Girven , Hannah F. Dugdale , Daniel J. Owens , David C. Hughes , Claire E. Stewart
DOI: 10.1002/JCP.25380
关键词: Myocyte 、 Endocrinology 、 Skeletal muscle cell differentiation 、 Cellular differentiation 、 Muscle cell differentiation 、 C2C12 、 Myogenesis 、 Myogenin 、 Biology 、 Internal medicine 、 Skeletal muscle
摘要: … in Fox03, Cfos, p53, and Bid … P38 MAPK substantially and significantly increased in both myoblasts and myotubes in the presence of TNF-α. Importantly, 20 mM l-glutamine reduced p38 …
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