作者: Brenda W. J. H. Penninx , Saskia M. F. Pluijm , Paul Lips , Richard Woodman , Kor Miedema
DOI: 10.1111/J.1532-5415.2005.00491.X
关键词: Prospective cohort study 、 Pediatrics 、 Poison control 、 Body mass index 、 Anemia 、 Incidence (epidemiology) 、 Geriatrics 、 Medicine 、 Risk factor 、 Longitudinal study 、 Physical therapy
摘要: OBJECTIVES: To examine whether anemia is associated with a higher incidence of recurrent falls. DESIGN: Prospective cohort study. SETTING: Community-dwelling sample in The Netherlands. PARTICIPANTS: Three hundred ninety-four participants aged 65 to 88 from the Longitudinal Aging Study Amsterdam. MEASUREMENTS: Anemia was defined according World Health Organization criteria as hemoglobin concentration less than 12 g/dL women and 13 men. Falls were prospectively determined using fall calendars that filled out weekly for 3 years. Recurrent fallers identified those who fell at least two times within 6 months during 3-year follow-up. RESULTS: Of 394 persons, 11.9% (18 29 men) had anemia. falls 38.3% anemic persons versus 19.6% nonanemic (P=.004). After adjustment sex, age, body mass index, diseases, significantly 1.91 greater risk (95% confidence interval=1.09-3.36). Poor physical function (indicated by muscle strength, performance, limitations) partly mediated association between CONCLUSION: Late-life common twice Muscle weakness poor performance appear mediate this