作者: Paulo H. M. Chaves , Bimal Ashar , Jack M. Guralnik , Linda P. Fried
DOI: 10.1046/J.1532-5415.2002.50313.X
关键词:
摘要: OBJECTIVES: The World Health Organization (WHO) and other currently used criteria for defining anemia in older women are mainly based on statistical distribution considerations. To explore their clinical appropriateness, we evaluated the relationship between hemoglobin (Hb) concentration, prevalent mobility difficulty, Summary Performance Score (SPS). DESIGN: Cross-sectional study. SETTING: Two population-based studies, Women's Aging Studies I II, Baltimore, Maryland. PARTICIPANTS: Six hundred thirty-three community-dwelling aged 70 to 80 with Hb levels obtained within 90 days from baseline assessment. MEASUREMENTS: Mobility difficulty (self-reported walking one-quarter of a mile or climbing 10 steps (primary outcome)). SPS, performance-based summary measure lower extremity function that combines results walking, chair stands, balance tests (secondary outcome). RESULTS: prevalence was not constant WHO “normal” range (12.0–16.0 g/dL). For example, 13.5 g/dL associated significantly than 12.0 (OR = 0.68, 95% CI 0.47–0.93), even after adjustment chronic diseases relevant health indicators. A consistent trend improvement scores increasing categories less g/dL, 13.0g/dL, 13.0–14.0 observed. CONCLUSION: Our findings raise two hypotheses: (1) perceived as “mildly-low” “low-normal” might have an independent, adverse effect function, (2) be suboptimal criterion women. Formal testing these hypotheses prove anemia- disability–related decision-making.