The anemia of senescence

摘要: A study of 196 healthy geriatric females and 26 males confirmed the high prevalence anemia in this population. Forty-two (21.4%) had a hematocrit less than 36% nine (34%) value 40%. careful evaluation, including therapeutic trial oral iron some subjects, made diagnosis deficiency only three chronic disease could be diagnosed two. No subject folate or B12 hemolytic was not present. Thus, most these lower due to commonly recognized causes. Further evaluation revealed leukopenia population; 30% having counts 5 X 10(3)/microliter 10% values 4 10(-3)/microliter. Of importance, leukocyte were significantly anemic subjects whom incidence neutropenia also demonstrated. This suggests that mechanisms unexplained is an overall reduction hematopoietic cell numbers. conclusion consistent with observation many aged have decreased ability mount adequate response infection. These findings suggest presence marks reserve provides clue those greatest risk inadequate stress.