Microfluidic Raman Spectroscopy for Bio-chemical Sensing and Analysis

摘要: The detection and analysis of bio-chemical analytes are important in the fields personal healthcare, drug development, environmental science, among others. field microfluidics aims to realize portable devices which can perform fast sensitive bioanalyte with minimal sample preparation. Raman spectroscopy is a powerful tool for analyte owing its high specificity ability multi-component an analyte. Combining would help achieve miniaturized analytical that may provide rich information about given However, low cross-section process demands special geometries such convergence. majority previous embodiments were restricted free-space geometry, limiting portability. recent studies, fiber-based system incorporated offers opportunity develop optofluidic devices. Here, we review various approaches used using detection, could be enhance sensitivity spectroscopy-based detection. This followed by detailed discussion systems.