An immunogenetic study of bullous pemphigoid with mucosal involvement in two siblings
作者： Akane Minagawa , Fuyuko Arakura , Hiroshi Koga , Yasutaka Tokuda , Hiroshi Koga
关键词: Immunology 、 Human leukocyte antigen 、 Dystonin 、 Hemidesmosome 、 Etiology 、 Pemphigoid 、 Autoantibody 、 Dermatology 、 Bullous pemphigoid 、 Sibling 、 Medicine
摘要: Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease mostly affecting the elderly. Patients with BP usually have autoantibodies against BP180 and/or BP230, which are major components of hemidesmosomes. Although etiology unclear, many studies shown that onset associated human leukocyte antigen (HLA) [1]. Here, we report two sibling patients carrying HLA-DQB1*03:01 and HLA-DRB1*04 alleles.Case 1: A 95-year-old Japanese man presented a 1-month [...]
springer.com
sci-hub.se 参考文章(10)
M. Hertl, T cell control in autoimmune bullous skin disorders Journal of Clinical Investigation. ,vol. 116, pp. 1159- 1166 ,(2006) , 10.1172/JCI28547
Banfield, Wojnarowska, Allen, George, Venning, Welsh, The association of HLA-DQ7 with bullous pemphigoid is restricted to men British Journal of Dermatology. ,vol. 138, pp. 1085- 1090 ,(1998) , 10.1046/J.1365-2133.1998.02350.X
Jee Bum Lee, Yuanlin Liu, Takashi Hashimoto, Cicatricial pemphigoid sera specifically react with the most C-terminal portion of BP180. Journal of Dermatological Science. ,vol. 32, pp. 59- 64 ,(2003) , 10.1016/S0923-1811(03)00035-5
Giovanni Di Zenzo, Sybille Thoma-Uszynski, Lionel Fontao, Valentina Calabresi, Silke C. Hofmann, Thomas Hellmark, Nathalie Sebbag, Cristina Pedicelli, Francesco Sera, Jean-Philippe Lacour, Jörgen Wieslander, Leena Bruckner-Tuderman, Luca Borradori, Giovanna Zambruno, Michael Hertl, Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid Clinical Immunology. ,vol. 128, pp. 415- 426 ,(2008) , 10.1016/J.CLIM.2008.04.012
L.R. Zakka, P. Reche, A.R. Ahmed, Role of MHC Class II genes in the pathogenesis of pemphigoid. Autoimmunity Reviews. ,vol. 11, pp. 40- 47 ,(2011) , 10.1016/J.AUTREV.2011.07.002
L Büdinger, L Borradori, C Yee, R Eming, S Ferencik, H Grosse-Wilde, H F Merk, K Yancey, M Hertl, Identification and characterization of autoreactive T cell responses to bullous pemphigoid antigen 2 in patients and healthy controls. Journal of Clinical Investigation. ,vol. 102, pp. 2082- 2089 ,(1998) , 10.1172/JCI3335
Aiko Okazaki, Sachiko Miyagawa, Yukio Yamashina, Wataru Kitamura, Toshihiko Shirai, Polymorphisms of HLA-DR and -DQ genes in Japanese patients with bullous pemphigoid. Journal of Dermatology. ,vol. 27, pp. 149- 156 ,(2000) , 10.1111/J.1346-8138.2000.TB02141.X
J. C. Delgado, D. Turbay, E. J. Yunis, J. J. Yunis, E. D. Morton, K. Bhol, R. Norman, C. A. Alper, R. A. Good, R. Ahmed, A Common Major Histocompatibility Complex Class II Allele HLA-DQB1 * 0301 is Present in Clinical Variants of Pemphigoid Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 8569- 8571 ,(1996) , 10.1073/PNAS.93.16.8569
Ada Lo Schiavo, Eleonora Ruocco, Gabriella Brancaccio, Stefano Caccavale, Vincenzo Ruocco, Ronni Wolf, Bullous pemphigoid: etiology, pathogenesis, and inducing factors: facts and controversies Clinics in Dermatology. ,vol. 31, pp. 391- 399 ,(2013) , 10.1016/J.CLINDERMATOL.2013.01.006
Ali Akbar Amirzargar, Zeinab Aryanian, Maede Rayati Damavandi, Nafiseh Esmaili, Hossein Mortazavi, Sheyda Chams-Davatchi, Maryam Daneshpazhoooh, Association between HLA-DQB1*03:01 and Bullous pemphigoid in Iranian patients. Iranian Journal of Immunology. ,vol. 10, pp. 1- 9 ,(2013)