fMRI studies of successful emotional memory encoding: A quantitative meta-analysis

摘要: Over the past decade, fMRI techniques have been increasingly used to interrogate neural correlates of successful emotional memory encoding. These investigations typically aimed either characterize contributions amygdala and medial temporal lobe (MTL) system, replicating results in animals, or delineate specific behavioral phenomena. It has remained difficult, however, synthesize these findings into a systems neuroscience account how networks across whole-brain support enhancing effects emotion on To this end, present study employed meta-analytic approach using activation likelihood estimates assess anatomical specificity reliability event-related activations related encoding for versus neutral information. The meta-analysis revealed consistent clusters within bilateral amygdala, anterior hippocampus, posterior parahippocampal gyrus, ventral visual stream, left lateral prefrontal cortex right parietal cortex. MTL wealth from animal literature linking regions arousal-mediated effects. consistency cortical targets, including visual, prefrontal, cortices, underscores importance generating hypotheses regarding their participation formation. In particular, we propose that interacts with structures promote enhancements perceptual processing, semantic elaboration, attention, which serve benefit subsequent material. may motivate future research modulation widespread implications cognition.