Deterioration in lung function following hemithorax irradiation for pleural mesothelioma

作者: Paula Maasilta

DOI: 10.1016/0360-3016(91)90054-8

关键词: AnesthesiaPneumonectomySurgeryMesotheliomaHypoxemiaDiffusing capacityThoraxLung injuryMedicineVital capacityLung

摘要: Thirty-four patients receiving high-dose hemithorax irradiation as part of the treatment for pleural mesothelioma were studied with regard to changes in lung function following irradiation, and these correlated radiologically-assessed injury. The latter was scored from 0 500 found be severe by 6 months (mean score 360), very 9 430), nearly total 12 480) after treatment. Forced vital capacity diffusing both showed a significant decline at 1.5-2 end radiotherapy thereafter up 1 year follow-up period. Neither variables could consistently changes. Hypoxemia pathological physiological shunting increased transiently 1-2 2 monitored. observed final effects are compatible loss on irradiated side. Before this form is used, should evaluated pneumonectomy.

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