1.22 – Biopsic Sampling (Cancer)

摘要: The aim of pathology is to diagnose disease through the study morphologic alterations in cells and tissues. This can be achieved using two approaches: histopathology cytopathology. Histopathology examination tissues, both macroscopic microscopic; cytopathology dissociated from their surrounding Both are widely use diagnosis prognostication cancer, determine presence extent neoplastic disease, assess tumor grading staging. In most specimens, microscopic accurate; however, selected cases with overlapping morphological features need a further step. step represented by ancillary tests: histochemistry, immunohistochemistry, molecular biology. These techniques, which have changed significantly, particular tests, based on detection abnormalities deoxyribonucleic acid (DNA) or ribonucleic (RNA), extracted accurately samples at forefront diagnostic modern pathology.