Studies on the regulation of leucine catabolism: Mechanism responsible for oxidizable substrate inhibition and dichloroacetate stimulation of leucine oxidation by the heart☆☆☆

作者: Ronald M. Sans , Walter W. Jolly , Robert A. Harris

DOI: 10.1016/0003-9861(80)90363-X

关键词: Oxoglutarate dehydrogenase complexLeucineBranched-chain alpha-keto acid dehydrogenase complexBiochemistryChemistryPyruvate dehydrogenase phosphatasePyruvate dehydrogenase complexPyruvate dehydrogenase kinaseDehydrogenasePyruvate decarboxylation

摘要: … Rat hearts perfused with [lJ4C]leucine but without any other exogenous substrate produce ‘*CO, at a rapid rate but release only small amounts of a-[lJ4C]ketoisocaproate into the …

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