Three New Sesquiterpene Glycosides from the Rhizomes of Trillium tschonoskii

摘要: Three new sesquiterpene glycosides, possessing a rare aglycone with sulfonyl between C-1 and C-15 positions, named 3-(3′E-7′R,8′-dihydroxy-4′,8′-dimethyl-3′-nonenyl)-2,5-dihydro-1,1-dioxo-thiophen 7′-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (1), 7′-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (2), 7′-O-β-d-glucopyranosyl-6′-O-acetyl-(1→4)-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (3), respectively, were isolated from the rhizomes of Trillium tschonoskii. Their structures established on basis spectroscopic data, including HR-ESI-MS, IR, 1D 2D NMR. The cytotoxic properties three compounds investigated using human hepatic L02 cells.