Sex-specific up-regulation of p50-associated COX-2 extragenic RNA (PACER) lncRNA in periodontitis.
作者： Arezou Sayad , Soudeh Ghafouri-Fard , Bahareh Shams , Shahram Arsang-Jang , Leila Gholami
DOI: 10.1016/J.HELIYON.2020.E03897
关键词: Immune disorder 、 Inflammation 、 Endocrinology 、 RNA 、 Medicine 、 Downregulation and upregulation 、 Tumor necrosis factor alpha 、 Beta (finance) 、 Periodontitis 、 Internal medicine 、 Gene expression
摘要: Abstract A number of recent studies have shown dysregulation some long non-coding RNAs (lncRNAs) in affected tissues or peripheral blood patients with periodontitis. In the current study, we investigated role TNF and HNRNPL related immunoregulatory (THRIL) p50-associated COX-2 extragenic RNA (PACER) lncRNAs We assessed expression these 30 tissue, control tissue samples, 23 samples from 18 healthy controls. Expression PACER was higher total compared controls (Posterior beta RE = 5.143, P value 0.001). However, when assessing its a gender-based manner, difference this lncRNA significant only among male subgroups 7.16,
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