Kinetic gating mechanism of DNA damage recognition by Rad4/XPC
作者： Xuejing Chen , Yogambigai Velmurugu , Guanqun Zheng , Beomseok Park , Yoonjung Shim
DOI: 10.1038/NCOMMS6849
关键词: Nucleotide 、 Biophysics 、 Protein structure 、 Nucleotide excision repair 、 DNA 、 DNA repair 、 Biochemistry 、 Gating 、 DNA damage 、 Biology 、 Xeroderma pigmentosum
摘要: … yeast XPC orthologue (… /XPC uses a kinetic gating mechanism whereby lesion selectivity arises from the kinetic competition between DNA opening and the residence time of Rad4/XPC …
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