ANTIBODIES TO BRADYKININ AND ANGIOTENSIN: A USE OF CARBODIIMIDES IN IMMUNOLOGY.
作者： T. L. Goodfriend , L. Levine , G. D. Fasman
DOI: 10.1126/SCIENCE.144.3624.1344
关键词: Antibody 、 Albumin 、 Bradykinin 、 Hapten 、 Carbodiimide 、 Chemistry 、 Immunology 、 Renin–angiotensin system 、 Biochemistry 、 Serum albumin 、 Antigen
摘要: Antibodies to bradykinin and angiotensin have been produced in rabbits by the use of conjugates containing albumin hapten, covalently bound. The water-soluble carbodiimide reagents provided an easy rapid method synthesis antigenic conjugates.
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John C. Sheehan, George P. Hess, A New Method of Forming Peptide Bonds Journal of the American Chemical Society. ,vol. 77, pp. 1067- 1068 ,(1955) , 10.1021/JA01609A099
D. H. Spackman, W. H. Stein, Stanford. Moore, Automatic recording apparatus for use in the chromatography of amino acids. Analytical Chemistry. ,vol. 17, pp. 1107- 1115 ,(1958) , 10.1021/AC60139A006
H. G. Khorana, The Chemistry of Carbodiimides. Chemical Reviews. ,vol. 53, pp. 145- 166 ,(1953) , 10.1021/CR60165A001
Eleanor Wasserman, L. Levine, Quantitative micro-complement fixation and its use in the study of antigenic structure by specific antigen-antibody inhibition. Journal of Immunology. ,vol. 87, pp. 290- ,(1961)
JOHN C. SHEEHAN, JOSEPH J. HLAVKA, The Use of Water-Soluble and Basic Carbodiimides in Peptide Synthesis Journal of Organic Chemistry. ,vol. 21, pp. 439- 441 ,(1956) , 10.1021/JO01110A017