Immunological Probes for the Bradykinin B2 Receptor. A Toolbox
DOI: 10.1016/B978-012249340-9/50008-5
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摘要: Publisher Summary This chapter provides an overview of the immunological tools for bradykinin (BK) B 2 receptor. Receptors kinins are classified as two major subtypes, 1 and , although other subtypes may exist. receptors activated by carboxyterminally truncated kinins, whereas BK kallidin (Lys-BK) receptor agonists. Molecular cloning has revealed primary structures identified them members G protein-coupled family, characterized seven membrane-spanning α-helices. In some tissues, expression is induced cytokines, such interleukin-1, thought to be expressed constitutively ubiquitous. The signaling pathways explored in chapter. An “toolbox” contains four sets gadgets: antiidiotypic antibodies that cross-reactive with receptor, antiligand cross-linked receptor-ligand complex, antipeptide predicted loops cross-react purified reviews procedures led these specific probes their applications localization functional analysis
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