High salt intake abolishes AT2-mediated vasodilation of pial arterioles in rats
作者： Sébastien Foulquier , François Dupuis , Caroline Perrin-Sarrado , Katy Maguin Gaté , Faten Merhi-Soussi
DOI: 10.1097/HJH.0B013E328347050E
关键词: Endocrinology 、 Angiotensin II receptor type 1 、 Cerebral circulation 、 Endothelium 、 Constriction 、 Angiotensin II 、 Internal medicine 、 Medicine 、 Vasodilation 、 Receptor 、 Peptide hormone
摘要: BackgroundAngiotensin II (Ang II) induces constriction (AT1) and dilation (AT2 receptors) of cerebral arterioles. High sodium intake changes in receptors expression loss AT2-mediated vasodilation extracerebral vessels. We investigated whether high salt modifies the res
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sci-hub.se 参考文章(36)
Henrik Wilms, Philip Rosenstiel, Thomas Unger, G??nther Deuschl, Ralph Lucius, Neuroprotection with angiotensin receptor antagonists: a review of the evidence and potential mechanisms. American Journal of Cardiovascular Drugs. ,vol. 5, pp. 245- 253 ,(2005) , 10.2165/00129784-200505040-00004
Enikö A Kramár, Joseph W Harding, John W Wright, Angiotensin II- and IV-induced changes in cerebral blood flow Regulatory Peptides. ,vol. 68, pp. 131- 138 ,(1997) , 10.1016/S0167-0115(96)02116-7
I J Perry, D G Beevers, Salt intake and stroke: a possible direct effect. Journal of Human Hypertension. ,vol. 6, pp. 23- 25 ,(1992)
Enzo R Porrello, LM Delbridge, Walter G Thomas, The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor Frontiers in Bioscience. ,vol. Volume, pp. 958- 972 ,(2009) , 10.2741/3289
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
Deborah M. Lenda, Bryan A. Sauls, Matthew A. Boegehold, Reactive oxygen species may contribute to reduced endothelium-dependent dilation in rats fed high salt. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 279, ,(2000) , 10.1152/AJPHEART.2000.279.1.H7
I Makino, K Shibata, Y Ohgami, M Fujiwara, T Furukawa, Transient upregulation of the AT2 receptor mRNA level after global ischemia in the rat brain. Neuropeptides. ,vol. 30, pp. 596- 601 ,(1996) , 10.1016/S0143-4179(96)90043-8
Siu-Lung Chan, Christine Capdeville-Atkinson, Jeffrey Atkinson, Red wine polyphenols improve endothelium-dependent dilation in rat cerebral arterioles. Journal of Cardiovascular Pharmacology. ,vol. 51, pp. 553- 558 ,(2008) , 10.1097/FJC.0B013E3181760FA5
Satomi Kagota, Akiko Tamashiro, Yu Yamaguchi, Reiko Sugiura, Takayoshi Kuno, Kazuki Nakamura, Masaru Kunitomo, Downregulation of vascular soluble guanylate cyclase induced by high salt intake in spontaneously hypertensive rats. British Journal of Pharmacology. ,vol. 134, pp. 737- 744 ,(2001) , 10.1038/SJ.BJP.0704300
Kevin Retailleau, Eric J. Belin de Chantemèle, Sébastien Chanoine, Anne-Laure Guihot, Emilie Vessières, Bertrand Toutain, Sébastien Faure, Zsolt Bagi, Laurent Loufrani, Daniel Henrion, Reactive Oxygen Species and Cyclooxygenase 2–Derived Thromboxane A2 Reduce Angiotensin II Type 2 Receptor Vasorelaxation in Diabetic Rat Resistance Arteries Hypertension. ,vol. 55, pp. 339- 344 ,(2010) , 10.1161/HYPERTENSIONAHA.109.140236