Waiting List Mortality Among Children Listed for Heart Transplantation in the United States

作者: Christopher S.D. Almond , Ravi R. Thiagarajan , Gary E. Piercey , Kimberlee Gauvreau , Elizabeth D. Blume

DOI: 10.1161/CIRCULATIONAHA.108.815712

关键词: MedicineHeart failureHeart transplantationInterquartile rangePediatricsEl NiñoHeart diseaseCohort studyPredictive value of testsExtracorporeal membrane oxygenation

摘要: Background— Children listed for heart transplantation face the highest waiting list mortality in solid-organ medicine. We examined since pediatric allocation system was revised 1999 to determine whether is prioritizing patients optimally and identify specific high-risk populations that may benefit from emerging cardiac assist devices. Methods Results— conducted a multicenter cohort study using US Scientific Registry of Transplant Recipients. All children <18 years age who were transplant between 2006 included. Among 3098 children, median 2 (interquartile range 0.3 12 years), weight 12.3 kg 5 38 kg); 1294 (42%) nonwhite; 1874 (60%) as status 1A (of whom 30% ventilated 18% on extracorporeal membrane oxygenation). Overall, 533 (17%) died, 1943 (63%) received transplants, ...

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