作者: Christopher S.D. Almond , Ravi R. Thiagarajan , Gary E. Piercey , Kimberlee Gauvreau , Elizabeth D. Blume
DOI: 10.1161/CIRCULATIONAHA.108.815712
关键词: Medicine 、 Heart failure 、 Heart transplantation 、 Interquartile range 、 Pediatrics 、 El Niño 、 Heart disease 、 Cohort study 、 Predictive value of tests 、 Extracorporeal membrane oxygenation
摘要: Background— Children listed for heart transplantation face the highest waiting list mortality in solid-organ medicine. We examined since pediatric allocation system was revised 1999 to determine whether is prioritizing patients optimally and identify specific high-risk populations that may benefit from emerging cardiac assist devices. Methods Results— conducted a multicenter cohort study using US Scientific Registry of Transplant Recipients. All children <18 years age who were transplant between 2006 included. Among 3098 children, median 2 (interquartile range 0.3 12 years), weight 12.3 kg 5 38 kg); 1294 (42%) nonwhite; 1874 (60%) as status 1A (of whom 30% ventilated 18% on extracorporeal membrane oxygenation). Overall, 533 (17%) died, 1943 (63%) received transplants, ...