Outcome of children with end-stage congenital heart disease waiting for cardiac transplantation

作者: Seema Mital , Linda J Addonizio , Jacqueline M Lamour , Daphne T Hsu

DOI: 10.1016/S1053-2498(02)00670-8

关键词:

摘要: Abstract Background: End-stage congenital heart disease (CHD) is a major indication for pediatric cardiac transplantation. The objective of the study was to evaluate pre-transplant outcome children with CHD. Methods: clinical profile and patients CHD Results: Mean age ( n = 46) 8.3 ± 8 years. Primary indications transplant were ventricular dysfunction in 36 (78%), failed Fontan (18%) severe hypoxemia 2 (4%) patients. Thirty-two Status 1 (70%), 14 5 de-listed. Twenty-nine 41 that remained listed survived transplant, 12 (29%) died waiting. Causes death sepsis failure (HF) 10 Eight multi-system organ failure, including 3 on mechanical circulatory support. time 29 28 days 94 176 days. at listing younger Group I (2.6 4 years) compared II (9.1 7 years, p Conclusions: Seventy-one percent transplant. Younger rapid onset HF significant risk factors mortality.

参考文章(14)
E. Pahl, D. Naftel, E. Frazier, W. R. Morrow, K. Rotondo, R. Chinnock, C. Canter, A. Rossi, I. Balfour, J. Fricker, V. Zales, C. Ramaciotto, D. Bernstein, D. C. McGiffin, J. K. Kirklin, J. Towbin, L. Addonizio, J. Alejos, D. Dodd, S. Bash, R. Shaddy, R. Caldwell, W. S. Ring, M. Boucek, R. Gajarski, R. Boucek, S. Webber, W. Moskowitz, Outcome of listing for heart transplantation in infants younger than six months: Predictors of death and interval to transplantation Journal of Heart and Lung Transplantation. ,vol. 16, pp. 1255- 1266 ,(1997)
Vaughn A. Starnes, Norman Shumway, Philip Oyer, Paul Pitlick, Daniel Bernstein, Edward Stinson, David Baum, Pediatric heart transplantation at Stanford: results of a 15-year experience. Pediatrics. ,vol. 88, pp. 203- 214 ,(1991)
WALTER H. MERRILL, WILLIAM H. FRIST, JAMES R. STEWART, ROBERT J. BOUCEK, DEBRA A. DODD, THEODORE E. EASTBURN, HARVEY W. BENDER, Heart transplantation in children. Annals of Surgery. ,vol. 213, pp. 393- 400 ,(1991) , 10.1097/00000658-199105000-00003
Daphne T. Hsu, Jan M. Quaegebeur, Robert E. Michler, Craig R. Smith, Eric A. Rose, Maryanne R. Kichuk, Welton M. Gersony, Judith F. Douglas, Linda J. Addonizio, Heart transplantation in children with congenital heart disease Journal of the American College of Cardiology. ,vol. 26, pp. 743- 749 ,(1995) , 10.1016/0735-1097(95)00253-Z
Jeffrey D Hosenpud, Leah E Bennett, Berkeley M Keck, Mark M Boucek, Richard J Novick, The registry of the international society for heart and lung transplantation: eighteenth official report—2001 Journal of Heart and Lung Transplantation. ,vol. 20, pp. 805- 815 ,(2001) , 10.1016/S1053-2498(01)00323-0
F Fontan, J W Kirklin, G Fernandez, F Costa, D C Naftel, F Tritto, E H Blackstone, Outcome after a "perfect" Fontan operation. Circulation. ,vol. 81, pp. 1520- 1536 ,(1990) , 10.1161/01.CIR.81.5.1520
Alfredo Trento, Bartley P. Griffith, Frederick J. Fricker, Robert L. Kormos, John Armitage, Robert L. Hardesty, Lessons learned in pediatric heart transplantation The Annals of Thoracic Surgery. ,vol. 48, pp. 617- 623 ,(1989) , 10.1016/0003-4975(89)90774-1
David N Rosenthal, Anne M Dubin, Clifford Chin, Daniel Falco, Pat Gamberg, Daniel Bernstein, Outcome while awaiting heart transplantation in children: a comparison of congenital heart disease and cardiomyopathy Journal of Heart and Lung Transplantation. ,vol. 19, pp. 751- 755 ,(2000) , 10.1016/S1053-2498(00)00135-2
Claude Chartrand, Pediatric cardiac transplantation despite atrial and venous return anomalies The Annals of Thoracic Surgery. ,vol. 52, pp. 716- 721 ,(1991) , 10.1016/0003-4975(91)90986-Z
Mark M Boucek, Albert Faro, Richard J Novick, Leah E Bennett, Bennie Fiol, Berkeley M Keck, Jeffrey D Hosenpud, The Registry of the International Society of Heart and Lung Transplantation: Third Official Pediatric Report-1999. Journal of Heart and Lung Transplantation. ,vol. 18, pp. 1151- 1172 ,(1999) , 10.1016/S1053-2498(99)00114-X