Viable offspring derived from fetal and adult mammalian cells.

摘要: Fertilization of mammalian eggs is followed by successive cell divisions and progressive differentiation, first into the early embryo subsequently all types that make up adult animal. Transfer a single nucleus at specific stage development, to an enucleated unfertilized egg, provided opportunity investigate whether cellular differentiation involved irreversible genetic modification. The offspring develop from differentiated were born after nuclear transfer embryo-derived line had been induced become quiescent. Using same procedure, we now report birth live lambs three new populations established mammary gland, fetus embryo. fact lamb was derived confirms did not involve modification material required for development term. fetal cells also reinforces previous speculation inducing donor quiescent it will be possible obtain normal wide variety cells.