A Case with Familial Mediterranean Fever which Responds Well to Adalimumab Treatment
作者： Özgür Ortancil , Aslan Sanli , Perihan Sapmaz Bulmuş , Selda Sarikaya
DOI: 10.5606/TJR.2011.024
关键词: Ankylosing spondylitis 、 Gastroenterology 、 Adalimumab 、 Internal medicine 、 Familial Mediterranean fever 、 Medicine
摘要: ©2011 Turkish League Against Rheumatism. All rights reserved. Ankilozan spondilit (AS) ailesel Akdeniz atesi (AAA)’ne eslik edebilir. Bu yazida eden AS'si olan ve tumor nekroz faktor alfa (TNF-α) inhibitoru (adalimumab) tedavisiyle basarili sekilde tedavi edilen 48 yasinda bir erkek AAA olgusu sunuldu. Hastaya TNF-α baslanmadan once kolsisin hastalik modifiye edici ilac (sulfasalazin leflunomid) tedavileri uygulandi fakat bu tedavilerle ataklari yeterli derecede kontrol altina alinamadi. Kolsisin birlikte adalimumab uygulandiginda, yillik takip esnasinda AS aktivitesinde duzelme saglandi ataklarinin sikligi siddeti azaldi. Geleneksel tedavilerin etkisiz kaldigi hastalarinda inhibitorlerinin secenegi olabilecegi dusuncesindeyiz.
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