New interest in an old disease: familial Mediterranean fever.

摘要: Familial Mediterranean fever (FMF) is characterized by recurrent attacks of and serositis. Identifying the mutated gene has shed light on pathogenesis disease. Typical FMF last 3 to 5 days. Arthritis present in almost half all patients localized ankle, knee or hip. Recently vasculitic features have been increasingly reported patients, it may be speculated that vasculitis constitutes a feature this Genetic analysis very important confirm diagnosis with European ancestry. However, at yield genetic testing not satisfactory; new sequencing techniques permitting more rapid screening definition mutations are necessary. Colchicine drug choice. A trial colchicine also help differential other periodic syndromes.