Oral misoprostol versus intramuscular oxytocin in the active management of the third stage of labour.
作者： E O Orji , S O Ogunniyi , O Kuti , E O Afolabi
DOI:
关键词: Anesthesia 、 Clinical trial 、 Vaginal delivery 、 Pregnancy 、 Randomized controlled trial 、 Nausea 、 Obstetrics 、 Misoprostol 、 Oxytocin 、 Umbilical cord 、 Medicine
摘要: Introduction Although the third stage of labour is usually uneventful, several significant complications may be encountered that lead to maternal morbidity and mortality, especially primary postpartum haemorrhage. The objective this study was compare 400 ug oral misoprostol with 10 IU intramuscular oxytocin in active management labour. Methods This a prospective randomised controlled clinical trial which 200 parturients at term who had vaginal delivery were randomly assigned into two groups: oxytocin, after baby clamping umbilical cord. outcome incidence Secondary outcomes included drop haemoglobin concentration 48 hours delivery, need for extra oxytocics, duration side effects oxytocics. These results subjected statistical analysis using chi-square test or student's t-test. Results No occurrence haemorrhage difference levels reported (p-value 0.49), no differences observed other secondary measures exception nausea, occurred solely group (4 percent, p-value 0.04). Conclusion Oral appeared as effective safe
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