Methods for directed differentiation of pluripotent stem cells to hla homozygous immune cells
作者： Deepika Rajesh , Wen Bo Wang , Sarah Burton , Xin Zhang , Maksym A. Vodyanyk
DOI:
关键词: Biology 、 Immune system 、 Myeloid 、 Cell biology 、 Directed differentiation 、 Induced pluripotent stem cell 、 Human leukocyte antigen 、 In vitro 、 Precursor cell 、 Haematopoiesis
摘要: Provided herein are methods for the efficient in vitro differentiation of HLA homozygous blood cell-derived pluripotent stem cells to hematopoietic precursor cells, and further into immune various myeloid or lymphoid lineages, particularly T NK dendritic cells. The may be maintained differentiated under defined conditions; thus, use mouse feeder serum is not required certain embodiments
lens.org 参考文章(48)
Michel Sadelain, Christopher C. Kloss, Maria Themeli, Effective generation of tumor-targeted t-cells derived from pluripotent stem cells ,(2014)
José Castell, María José Gómez-Lechón, In vitro methods in pharmaceutical research Academic Press. ,(1997)
Yoichi Sakata, Toshiaki Tabata, Tsukasa Ohmori, Katsuyuki Mitomo, Mamoru Hasegawa, Therapeutic method for blood coagulation disorder ,(2006)
Linda Koonce, Norma L. Trolinder, In planta method for the production of transgenic plants ,(1998)
Robert Lanza, Shi-Jiang Lu, Hemangio colony forming cells and non-engrafting hemangio cells ,(2009)
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
David T. Denhardt, Raymond L. Rodriguez, Vectors : a survey of molecular cloning vectors and their uses Butterworths. ,(1988)
Scott H. Wittkopp, Craig S. Ross, Edward W. Mellet, Eight speed dual clutch transmission ,(2011)
Lawrence H. Kedes, Charles P. Shuler, Theodore I. Prigozy, Producing a protein in a mammal by injection of a DNA-sequence into the tongue ,(1994)
James M. Dunwell, Ronald A. Coffee, Transformation of plant cells ,(1991)