The safety and efficacy of stereotactic biopsy for intracranial lesions.

摘要: BACKGROUND Stereotactic brain biopsy is considered by many physicians to have significant morbidity and mortality rates with a high risk of sampling error resulting in misdiagnosis. The technical aspects necessary perform the procedure safely effectively are unfamiliar most physicians. METHODS After reporting his initial results stereotactic biopsy, several modifications were implemented author improve morbidity, mortality, diagnostic yield rates, including complex surgical planning regard patient selection, trajectory, imaging technique, target choice, intraoperative pathologic review. implementing these examined retrospectively 134 consecutive biopsies. RESULTS One hundred thirty-four biopsies performed 122 patients. Computed tomography guidance was used 85 patients (63%) magnetic resonance 49 (37%). Sixty-four lesions (48%) located right hemisphere, 61 (45%) left, 9 (7%) midline. common diagnoses included 62 malignant tumors (46%), 24 benign (18%), 23 neurologic disorders (17%), 20 infections (15%). Five (4%) did not demonstrate process for an overall 96%. Reasons failure lesion location adjacent ventricular system, inaccurate targeting, inability penetrate tumor. One sustained deficit after rate 0.7% one fatal hemorrhage during vascular tumor 0.7%. These comparable those reported 7471 (current series included) which 3.5%, 0.7%, 91%. CONCLUSIONS Stereotactic extremely safe effective evaluating intracranial lesions. Complex can decrease potential complications use examination this procedure. Cancer 1998;82:1749-55. © 1998 American Society.