Trial watch: BTK inhibitor shows positive results in B cell malignancies.

作者: Charlotte Harrison

DOI: 10.1038/NRD3656

关键词: Clinical trialBruton's tyrosine kinaseB cellImmunologyB-cell lymphomaTyrosine kinaseHematologyInternal medicineMedicine

摘要: Preliminary clinical trial data recently presented at the American Society of Hematology meeting showed that Bruton's tyrosine kinase (BTK) inhibitor PCI-32765 was effective in treating several types B cell lymphoma. Furthermore, is centre a deal — worth up to US$975 million between drug's developer Pharmacyclics and Janssen Biotech.

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