Alpha lipoic acid attenuates hypoxia-induced apoptosis, inflammation and mitochondrial oxidative stress via inhibition of TRPA1 channel in human glioblastoma cell line

作者: Haci Ahmet Deveci , Yener Akyuva , Gökhan Nur , Mustafa Nazıroğlu

DOI: 10.1016/J.BIOPHA.2018.12.077

关键词: ApoptosisGlutathione peroxidaseChemistryGlutathioneCancer cellReactive oxygen speciesPharmacologyCaspase 3Oxidative stressHypoxia (medical)

摘要: … cancer cells the induction of apoptosis [7]. Mitochondrial oxidative stress in cancer cells can be … The CoCl 2 -induced mitochondrial oxidative stress was blocked by the ROS scavengers …

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