Human alpha-feto-protein.

摘要: This general review of human alpha fetoprotein (AFP) is divided into 2 parts: 1) Techniques for AFP isolation (biochemical and immunochemical) described stepwise. A chart shows preparation from fetal serum the main biochemical physicochemical components are presented tabularly as culled other studies which demonstrated in biological fluids. 2) The biosynthesis comprises bulk discussion. Since physiological during neonatal life disappears shortly after birth its reappearance adult signals a misfunction. For example conditions reappearing primary liver cancer analyzed well occurrence some tumoral diseases including teratoblastoma gastrointestinal tract nontumoral hepatic (e.g. hepatitis). Genetic (cell differentiation) molecular multiplication) level hypotheses regarding AFPs summarized; pregnancy trace amounts normal individuals receives little attention this review.